Atypical Porcine Pestivirus Molecular Evolution within a Persistently Infected Swine Farm
نویسندگان
چکیده
منابع مشابه
Atypical Porcine Pestivirus as a Novel Type of Pestivirus in Pigs in China
Pestiviruses are highly variable RNA viruses. A growing number of novel pestiviruses has been discovered in domestic and wild species in the last two decades. Recently, a novel atypical porcine pestivirus (APPV) linked with the development of congenital tremor (CT) in neonatal pigs was described in Europe and the Americas. Here, the first Asian APPV complete polyprotein coding sequence was asse...
متن کاملMucosal disease-like syndrome in a calf persistently infected by Hobi-like pestivirus.
A calf persistently infected with Hobi-like pestivirus displayed severe clinical signs and subsequently died. Gross lesions and histopathological changes were suggestive of hemorrhagic and necrotic inflammation involving several tissues. A Hobi-like pestivirus pair was isolated from the dead calf, i.e., cytopathogenic (CP) and noncytopathogenic (NCP) strains strictly related to each other and t...
متن کاملAtypical Porcine Pestivirus: A Possible Cause of Congenital Tremor Type A-II in Newborn Piglets
Congenital tremor type A-II in piglets has been regarded as a transmissible disease since the 1970s, possibly caused by a very recently-described virus: atypical porcine pestivirus (APPV). Here, we describe several strains of APPV in piglets with clinical signs of congenital tremor (10 of 10 farms tested). Piglets on a farm with no history of congenital tremor were PCR-negative for the virus. T...
متن کاملDiscovery of a novel putative atypical porcine pestivirus in pigs in the USA.
Pestiviruses are some of the most significant pathogens affecting ruminants and swine. Here, we assembled a 11 276 bp contig encoding a predicted 3635 aa polyprotein from porcine serum with 68 % pairwise identity to that of a recently partially characterized Rhinolophus affinis pestivirus (RaPV) and approximately 25-28 % pairwise identity to those of other pestiviruses. The virus was provisiona...
متن کاملCongenital infection with atypical porcine pestivirus (APPV) is associated with disease and viral persistence
In 2013, several Austrian piglet-producing farms recorded outbreaks of action-related repetitive myoclonia in newborn piglets ("shaking piglets"). Malnutrition was seen in numerous piglets as a complication of this tremor syndrome. Overall piglet mortality was increased and the number of weaned piglets per sow decreased by more than 10% due to this outbreak. Histological examination of the CNS ...
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ژورنال
عنوان ژورنال: Proceedings
سال: 2020
ISSN: 2504-3900
DOI: 10.3390/proceedings2020050029